to drive someone nuts

'Sacar de quicio' is a Spanish phrase that translates to 'to drive someone nuts' in English. It is usually used to express the action of annoying or frustrating someone to the point of losing their patience. It's often utilized in situations of intense irritation or aggravation, similar to the English phrases 'driving me up the wall' or 'pushing my buttons'. So when someone 'saca de quicio', they’re engaging in some form of provocation or harassment that is likely to garner a strong reaction.